International Circulation: How do you see the future of using poly-pill in the secondary prevention of cardiovascular diseases?
Sidney Smith: I think secondary prevention offers the greatest opportunity for the poly-pill. Patients are more willingly to take one pill than taking 3 or 4 pills. There are some hurtles to overcome however. That is the dose of the ingredients since some patients may need to take a higher dose than others. Also, by putting all the drugs in one pill you need to be sure that they have the same effect as if taken singly. In general, I believe the poly-pill’s greatest potential may lie in treating people who have known disease in terms of having a real effect. A number of studies are underway to show whether it does make a difference. It will be a couple of years before we know for sure.
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